Saturday, 8 March 2014

HEALTH ALERT: HIGH VITAMIN D LEVELS DOUBLE BREAST CANCER SURVIVAL

HIGH VITAMIN D LEVELS DOUBLE BREAST CANCER SURVIVAL


In previous studies, Cedric F. Garland, Ph.D., at the UC San Diego School of Medicine’s department of  family and preventative medicine, showed that low vitamin D levels were linked to a high risk of premenopausal breast cancer. The finding prompted him to question the relationship between 25-hydroxyvitamin D—a metabolite produced by the body from the ingestion of vitamin D—and breast cancer survival rates.

For this study, Garland and colleagues performed a statistical analysis of five studies of 25-hydroxyvitamin D obtained at the time of patient diagnosis and their 9-year follow-up. Combined, the studies included 4,443 breast cancer patients.

“Vitamin D metabolites increase communication between cells by switching on a protein that blocks aggressive cell division," he said. “As long as vitamin D receptors are present tumor growth is prevented and kept from expanding its blood supply. Vitamin D receptors are not lost until a tumor is very advanced. This is the reason for better survival in patients whose vitamin D blood levels are high."

Women in the high serum group had an average level of 30 nanograms per milliliter (ng/ml) of 25-hydroxyvitamin D in their blood. The low group averaged 17 ng/ml. The average level in patients with breast cancer in the United States is 17 ng/ml.

A study published in January 2104 in the Journal of Clinical Endocrinology and Metabolism foundchildren are likely to have stronger muscles if their mothers had a higher level of vitamin D in their body during pregnancy. Low vitamin D concentrations are common among young women, suggesting women should consume higher amounts of vitamin D during pregnancy.

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